The Newbury and District clinical commissioning group (CCG) is set to merge with three others from next April with the aim of improving practice and cutting costs.
It is proposing joining forces with the South Reading, North and West Reading and Wokingham CCGs to create one group covering Berkshire West.
GP practices across the four CCGs voted last month in favour of the plans, with NHS England due to make a final decision on the merger in September.
Potential benefits of a merger include reducing the workload on staff who already work across the four CCGs, and improving the quality of the service the CCGs provide.
In terms of funding, an estimated £150,000 to £200,000 would be saved each year through removing duplication of work.
That comes as the CCGs anticipate having to cut costs by around £600,000 by 2020/21.
A joint statement from the four CCGs said: “Running four separate CCGs has resulted in a lot of duplication and inefficiency.
“The CCGs now want to focus clinical and managerial leadership on developing new primary care organisations that brings groups of GP practices together and develop an accountable care system with other partners.
“The four localities will ensure that our commissioning will remain locally sensitive, and we maintain close working relationships with GP practices, local authorities, Healthwatch and other stakeholders.”
CCGs were set up in 2013 with responsibility for the planning and commissioning of healthcare services for their local area.
There are currently 207 CCGs in England, seven of which are in Berkshire.
Andrew Sharp, chief executive of Healthwatch West Berkshire, welcomed the proposals.
He said: “Certainly from an administrative and management perspective in an ever-complex health service, it makes perfect sense.
“We were going through this nonsense of the senior management team having to hold four board meetings a month that were practically identical except for the small portion of local stuff.
“When you look at that, you’ve got the most important management team frankly wasted and repeating themselves, when they could be getting on with more important stuff.
“We just need to ensure that it keeps the local feel, with local GPs and local knowledge feeding directly in.”
Providing the merger is approved, the Berkshire West CCG would operate in shadow form from October, ahead of becoming fully operational on April 1 next year.